MLP-DT: A Deep Learning Model for Early Prediction of Diabetes and Thyroid Disorders

CHAIB Aouatef, DJAMA Ouahiba, MESSAOUDI Saber

Abstract


In this paper we present an intelligent and automated system for controlling
diabetes and thyroid disorders. This system is designed to self-diagnose autoimmune
diseases as early as possible in order to treat them quickly and thus
slow down or stop their progression and thus provide a tool for self-control of
diseases. Our system is based on Deep neural networks (DNNs), it contains several
layers and it is classified as MLP (Multi-Layer Perceptron). The proposed
model called Multi-Layer Perceptron model for early prediction of Diabetes and
Thyroid disorders (MLP-DT) uses a set of biomedical variables, allowing the
system to formulate personalized treatment recommendations. To improve diagnostic
accuracy and facilitate early screening, the system also incorporates
machine learning techniques. The optimization in MLP-DT is provided by the
Adam Optimizer algorithm, it is always applied to adjust the weights of the
three hidden layers and the output layer (Sigmoid or Softmax). Experimental
results demonstrate that the proposed MLP-DT model achieves reliable predictive
performance and supports effective early screening of diabetes and thyroid
disorders. These findings highlight the potential of the proposed approach as
an intelligent decision-support tool for personalized healthcare and preventive
medicine.


Keywords


MLP-DT; Artificial Intelligence; Neural Network; Adam Optimizer; Early Diagnosis; Diabetes; Thyroid Disorders

Full Text:

PDF

References


J. Flore, C. Avila, and R. Springal, “Usefulness of Easy-to-Use Risk Scoring Systems Rated in the Emergency Department to

Predict Major Adverse Outcomes in Hospitalized COVID-19 Patients,” Journal of Clinical Medicine, vol. 10, no. 3657, 2021, doi:

3390/jcm10163657.

J. London and L. Mouthon, “Maladies rares en m´edecine d’urgence,” in Service de m´edecine interne, Hˆopital Cochin, Centre

de R´ef´erence pour les vascularites n´ecrosantes et la scl´erodermie syst´emique, AP-HP et Universit´e Paris Descartes, 2015, ISBN

-2-8178-0349-4.

G. J. Tob´on, J.-O. Pers, C. A. Ca˜nas, A. Rojas-Villarraga, P. Youinou, and J.-M. Anaya, “Autoimmunity Reviews,” Elsevier, 2012,

doi: 10.1016/j.autrev.2011.10.004.

G. Chabchoub, M. Mnif, A. Maalej, N. Charfi, H. Ayadi, and M. Abid, “ ´ Etude ´epid´emiologique des maladies auto-immunes

thyro¨ıdiennes dans le sud tunisien,” Annales d’Endocrinologie, vol. 67, pp. 591–595, 2006, doi: 10.1016/s0003-4266(06)73012-8.

Hassani, F. A., Bensouda, M., & Ouahabi, P. H. El, ”Carcinome papillaire d´evelopp´e sur une ectopie thyro¨ıdienne lat´erocervicale,”

Annales d’Endocrinologie, vol. 78, no. 4, p. 348, 2017. doi:10.1016/j.ando.2017.07.432.

Bouadjila, L., & Taleb, Z., ”Le portail NCBI : base de donn´ees bioinformatique cl´e en biotechnologies,” Th`ese de doctorat, Universit

´e Mohamed BOUDIAF de M’Sila, 2019.

Boubendir, A., Khelili, K., & Hamidechi, M. A., ”Importance of the bioinformatics tool in the confirmation of bacterial species

isolated from raw milk,” Sciences & Technologie C, Biotechnologies, no. 42, pp. 38–43, 2016. doi:10.1007/s13213-015-1163-5.

Dayhoff, M., Schwartz, R., & Orcutt, B., ”A model of evolutionary change in proteins,” 1978.

Corpet, F., & Chevalet, C., ”Analyse informatique des donn´ees mol´eculaires,” Productions Animales, HS 2000, pp. 191–195, 2000.

doi:10.20870/productions-animales.2000.13.hs.3837.

Ouzounis, C. A., & Valencia, A., ”Early bioinformatics: the birth of a discipline—a personal view,” Bioinformatics, vol. 19, no. 17,

pp. 2176–2190, 2003. doi:10.1093/bioinformatics/btg309.

Bhavsar, K. A., et al., ”Medical diagnosis using machine learning: a statistical review,” Computers, Materials and Continua, vol.

, no. 1, pp. 107–125, 2021. doi:10.32604/cmc.2021.014604.

Min, S., Lee, B., & Yoon, S., ”Deep learning in bioinformatics,” Briefings in Bioinformatics, vol. 18, no. 5, pp. 851–869, 2017.

doi:10.1093/bib/bbw068.

Larra˜naga, P., et al., ”Machine learning in bioinformatics,” Briefings in Bioinformatics, vol. 7, no. 1, pp. 86–112, 2006.

doi:10.1093/bib/bbk007.

Khandare, S. B., & Chandak, M. B., ”Techniques of deep learning neural network-based building feature extraction from remote

sensing images: a survey,” International Journal of Information and Communication Technology, vol. 14, no. 2, pp. 614–624, 2025.

doi:10.11591/ijict.v14i2.pp614-624.

Badrinath, G., & Gupta, A., ”A survey on ransomware detection using AI models,” International Journal of Information and

Communication Technology, vol. 14, no. 3, pp. 1085–1094, 2025. doi:10.11591/ijict.v14i3.pp1085-1094.

Zhang, Y., Yan, Y., Kumar, R. L., & Juneja, S., ”Improving college ideological and political education based on deep learning,” Int.

J. Information and Communication Technology, vol. 24, no. 4, pp. 431–447, 2024. doi:10.1504/IJICT.2024.138778.

Ponti, F., Frezza, F., Simeoni, P., & Parisi, R., ”A Generalized Learning Approach to Deep Neural Networks,” Journal of Telecommunications

and Information Technology, no. 3, 2024. doi:10.26636/jtit.2024.3.1454.

Aggarwal, R., et al., ”Diagnostic accuracy of deep learning in medical imaging: a systematic review and meta-analysis,” NPJ Digital

Medicine, vol. 4, p. 65, 2021. doi:10.1038/s41746-021-00438-z.

Azdine, B., & El Kabbouri, M., ”L’analyse sentimentale et l’apprentissage automatique: M´ethodes hybrides et perspectives futures,”

Int. J. Accounting, Finance, Auditing, Management and Economics, vol. 6, no. 1, pp. 166–190, 2025. doi:10.1515/9782760525702-

Bakator, M., & Radosav, D., ”Deep learning and medical diagnosis: A review of literature,” Multimodal Technologies and Interaction,

vol. 2, no. 3, p. 47, 2018. doi:10.3390/mti2030047.

Taud, H., & Mas, J. F., ”Multilayer perceptron (MLP),” in Geomatic Approaches for Modeling Land Change Scenarios, Springer,

Cham, 2017, pp. 451–455. doi:10.1007/978-3-319-60801-3 27.

Naskath, J., Sivakamasundari, G., & Begum, A. A. S., ”A study on different deep learning algorithms used in deep neural nets: MLP,

SOM and DBN,” Wireless Personal Communications, vol. 128, no. 4, pp. 2913–2936, 2023. doi:10.1007/s11277-022-10079-4.

Bisong, E., ”The Multilayer Perceptron (MLP),” in Building Machine Learning and Deep Learning Models on Google Cloud

Platform, Apress, Berkeley, 2019, pp. 401–405. doi:10.1007/978-1-4842-4470-8 31.

Ifriza, Y. N., et al., ”Optimization Artificial Neural Network (ANN) Models with Adam Optimizer to Improve Customer

Satisfaction Business Banking Prediction,” Jurnal Teknik Informatika (Jutif), vol. 6, no. 3, pp. 1419–1430, 2025.

doi:10.52436/1.jutif.2025.6.3.4776.

Salihu, S. A., et al., ”Detection and Classification of Potato Leaves Diseases Using Convolutional Neural Network and Adam

Optimizer,” Procedia Computer Science, vol. 258, pp. 2–17, 2025. doi:10.1016/j.procs.2025.04.159.

Chen, G. D., et al., ”Associations between thyroid function and gestational diabetes mellitus in Chinese pregnant women: a retrospective

cohort study,” BMC Endocrine Disorders, vol. 22, no. 1, p. 44, 2022. doi:10.1186/s12902-022-00959-y.

Zou, C., et al., ”Association of maternal thyroid function and gestational diabetes with pregnancy outcomes: a retrospective cohort

study,” Frontiers in Endocrinology, vol. 16, p. 1555409, 2025. doi:10.3389/fendo.2025.1555409.

Zhang, Z., et al., ”Machine learning prediction models for gestational diabetes mellitus: meta-analysis,” Journal of Medical Internet

Research, vol. 24, no. 3, p. e26634, 2022. doi:10.2196/26634.

Zaky, H., et al., ”Machine learning-based model for the early detection of Gestational Diabetes Mellitus,” BMC Medical Informatics

and Decision Making, vol. 25, no. 1, p. 130, 2025. doi:10.1186/s12911-025-02947-3.

Zhao, H., et al., ”Diagnosis of thyroid disease using deep convolutional neural network models applied to thyroid scintigraphy

images: a multicenter study,” Frontiers in Endocrinology, vol. 14, p. 1224191, 2023. doi:10.3389/fendo.2023.1224191.




DOI: http://doi.org/10.11591/ijict.v15i2.pp778-788

Refbacks

  • There are currently no refbacks.


Copyright (c) 2026 Institute of Advanced Engineering and Science

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

The International Journal of Informatics and Communication Technology (IJ-ICT)
p-ISSN 2252-8776, e-ISSN 2722-2616
This journal is published by the Intelektual Pustaka Media Utama (IPMU).

Web Analytics View IJICT Stats